The skin’s endocannabinoid system helps to regulate various cellular processes including proliferation,differentiation, and apoptosis or cell death. Thus, imbalance of this system is responsible for the occurrence of chronic skin conditions such as advanced aging, psoriasis and eczema, and developing targeted cannabinoid therapies may help to control the root of optimal skin health.

Many skin conditions are inflammatory in nature and the anti-inflammatory effects of cannabinoids on skin cells have been demonstrated. The active ingredients in cannabis, such as THC and CBD, can interact with the ECS in the skin. THC binds to the CB1 receptor, while CBD binds to the CB2 receptor.

These interactions can lead to a variety of effects, including pain relief, itch relief, inflammation reduction and overall balance and support to other skin systems.